Five-time U.S. Open winner Federer was given a probable quarterfinal beside two-time French Open second best Robin Soderling in Thursday's draw. The No. 5-seeded Soderling disturb Federer in the quarterfinals in Paris this year, stopping Federer's record run of reaching at least the semifinals at 23 following Grand Slam tournaments.
The other men's matchups in the quarterfinals could be No. 1-seeded Rafael Nadal next to No. 8 Fernando Verdasco, two-time major finalist Andy Murray against Wimbledon runner-up Tomas Berdych, and No. 3 Novak Djokovic against No. 6 Nikolay Davydenko or No. 9 Andy Roddick.

"I know if I play well that I can beat anybody out there," said Clijsters, who also won the 2005 Open, "so that's what I'm going to try to accomplish."
Murray, hoping to turn into the first British man since 1936 to be successful a Grand Slam title, could meet No. 20-seeded Sam Querrey of the United States in the fourth round. Another American, Wimbledon marathon man John Isner, is seeded 18th and also is in that quarter of the draw.
In the semifinals, Murray was drawn to meet Nadal, who lost in that round in New York each of the past two years and is trying to complete a career Grand Slam by winning the U.S. Open for the first time.
"Over the last three years here, I've only lost to one player -- Federer -- and that gives me enough reason to believe I can go far this year," Djokovic said, "because I like the courts, I like the feel here. I just like the tournament -- it's appropriate to my game, and to my personality."
Federer could face another common enemy in the third round: 2001 U.S. Open and 2002 Wimbledon champion Lleyton Hewitt. Federer beat Hewitt in the 2004 U.S. Open final, part of a 15-match, opposite winning line for Federer -- which ended when Hewitt hit him in the final of a grass-court tournament at Halle, Germany, in June.
Williams' older sister Venus, who is seeded No. 3, could face an intriguing matchup in the third round against No. 32-seeded Tsvetana Pironkova of Bulgaria. Pironkova has won two of her previous three matches against Venus Williams, including a straight-set upset in the Wimbledon quarterfinals June 29.
The U.S. Open begins Monday, and Williams will have gone more than two months without a match by the time she meets her first-round opponent, Roberta Vinci of Italy, who is 1-7 for her career at Flushing Meadows.